I-Vitamin E yigama elihlangene lezinto eziyisi-8 ezihlobene ezakhiwe i-tocopherol ne-tocotrienol. Bayisigaba samafutha-amavithamini ancibilikayo anomsebenzi wokulwa ne-antioxidant. Phakathi kwalezi zingxubevange, ngenxa yokuthi umzimba womuntu uthatha ngokukhethekile futhi ugaye -i-tocopherol, -i-tocopherol inokutholakala kwe-bioavailability okukhulu kakhulu futhi kuhlolisiswe kakhulu.
I-Alpha-tocopherol kuthiwa ingamafutha abaluleke kakhulu-e-soluble antioxidant. Isusa ama-radical free intermediate futhi imise ukukhula kweketango lama-radicals mahhala, ngaleyo ndlela ivikele ulwelwesi lweseli ekubhujisweni kwe-lipid peroxides ekhiqizwa ukusabela kweketango le-peroxidation. Umphumela we-oxidation state -i-tocopherol free radicals ingaba Amanye ama-antioxidants afana ne-vitamin C, i-retinol noma i-panthenol ayancishiswa ukuze abuyele esimweni esinciphile esisebenzayo futhi aqhubeke edlala indima yokulwa ne-antioxidant. Ucwaningo oluhlobene luthole ukuthi -i-tocopherol kunamanzi{7}}ama-antioxidant ancibilikayo angavikela ngempumelelo amaseli angenayo i-glutathione peroxidase 4 (GPX4) ekufeni, futhi i-GPX4 ukuphela kwamandla owaziwayo I-enzyme eyehlisa ngempumelelo i-lipid peroxides ku-biofilms. Lolu cwaningo luthole ukuthi luhambisana nomthelela we-antioxidant -we-tocopherol kulwelwesi lwamaseli.
Kodwa-ke, akukacaci ngendima nokubaluleka kwamanye amavithamini E amaningi emiphumeleni ye-antioxidant. Nakuba -i-tocopherol ikwazi ukusebenzisana nezinto ze-electrophilic mutagenic njenge-nucleophile, futhi i-tocotrienol idlala indima ebalulekile ekuvikeleni izinzwa emonakalweni, iwusizo kwamanye amavithamini E ambalwa ngaphandle kokuthi -i-tocopherol. Indima yama-antioxidants ayikaqondwa kahle.
